Editors: Fabienne T.-Cottier, Ger v. Zandbergen

Neutrophils in Infectious Diseases

eBook: US $39 Special Offer (PDF + Printed Copy): US $90
Printed Copy: US $71
Library License: US $156
ISBN: 978-1-60805-382-7 (Print)
ISBN: 978-1-60805-023-9 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080502391110101

Introduction

Host defense to intracellular pathogens depends upon both innate and adaptive cell-mediated immune responses. Polymorphonuclear neutrophil leukocytes which belong to the innate immune system are the first cells that are recruited massively within hours of microbial infection. The importance of neutrophils in the development of an immune response is only emerging as they have long been considered by immunologists as short lived, non-dividing cells, of poor interest. Now, neutrophils are emerging as key components of the inflammatory response, and are shown to have immunoregulatory roles in microbial infections. The impact of neutrophils on cells present at the site of infection is only beginning to be studied and deserves more attention. This e-book provides an overview of the recent advances made in the field of neutrophil biology and motions towards some of the exciting new directions in which neutrophil research is moving.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, Chemical Abstracts, EBSCO.

Foreword

- Pp. i
Werner Solbach
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Preface

- Pp. ii
Fabienne Tacchini-Cottier and Ger van Zandbergen
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Contributors

- Pp. iii-iv (2)
Fabienne Tacchini-Cottier and Ger van Zandbergen
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Neutrophils and Extracellular Traps in Microbial Infections

- Pp. 3-10 (8)
Volker Brinkmann

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Imaging Neutrophil-Pathogen Interactions in vivo

- Pp. 11-19 (9)
Sylvia Münter, Claudia Kuss, Markus Meissner and Friedrich Frischknecht

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Neutrophils in the Context of Polymicrobial Sepsis

- Pp. 20-36 (17)
Danielle G. Souza, José C. Alves-Filho, Fernando Q. Cunha, Cristiano X. Lima and Mauro M. Teixeira

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The Role of Neutrophils in Chlamydia pneumoniae Infection: First Line of Defense or the Gateway for Systemic Dissemination?

- Pp. 37-41 (5)
Ger van Zandbergen and Jan Rupp

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Neutrophils in Mycobacterial Infections

- Pp. 42-48 (7)
Angelo Martino, Edgar Badell and Nathalie Winter

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Role of Neutrophils in the Early Shaping of the Leishmania major Specific Immune Response in Experimental Murine Cutaneous Leish

- Pp. 49-58 (10)
Angelo Martino, Edgar Badell, Nathalie Winter, Mélanie Charmoy, Geneviève Milon and Fabienne Tacchini-Cottier

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Understanding Neutrophil Function During Toxoplasma gondii Infection

- Pp. 59-66 (8)
Eric Y. Denkers

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Neutrophils as Potential Safe Niche for Leishmania and Anaplasma

- Pp. 67-76 (10)
Ger van Zandbergen, Elena Bank, Martina Behnen, Matthias Klinger and Tamas Laskay

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Index

- Pp. 77-79 (3)
Fabienne Tacchini-Cottier and Ger van Zandbergen
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