Editor: Herman Cheung

Stem Cell & Regenerative Medicine

eBook: US $32 Special Offer (PDF + Printed Copy): US $144
Printed Copy: US $128
Library License: US $128
ISBN: 978-1-60805-697-2 (Print)
ISBN: 978-1-60805-008-6 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080500861100101

Introduction

The potential use of stem cells in transplantation for the purpose of tissue regeneration is an exciting area of research currently undergoing rapid development. Implantation of human embryonic or autologous, ex vivo-expanded adult stem cells, particularly in older individuals, could circumvent the limited availability of organs/tissues as well as prevent complications related to immune rejection and disease transmission. Musculoskeletal tissue degeneration is closely associated with aging. Strategies employing autologous adult MSCs from older individuals for transplantation in order to regenerate their own ailing organ or tissues require that we vigorously define MSCs capacity to maintain growth potential and differentiation potential into the desirable cell lineages. We are currently restricted by the limited knowledge about physical parameters, such as biomechanical forces, that influence MSC growth and differentiation capacities. This is particularly important for MSCs isolated from older individuals, for whom little information is available. This special volume aims to serve as an impetus in generating more interest among stem cell researchers and biotechnologists to improve and develop the cell-based therapies of damaged tissue using stem cells.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, EBSCO.

Contributors

Editor(s):
Herman Cheung
Miami VA Medical Center
USA




Contributor(s):
Akshay Anand
Professor, Dept. of Neurology
Post Graduate Institute of Medical Education and Research
Chandigarh
India


Herman S. Cheung
James L. Knight Professor, Dept. of Biomedical Engineering
1251 Memorial Drive, Coral Gables, FL & Geriatrics Research, Education and Clinical Center and Research Service, Miami VA Healthcare System, 1201 NW 16 Street,
Miami
FL
USA


Kevin Curtis
Departments of Medicine and Biochemistry & Molecular Biology
University of Miami Leonard M. Miller School of Medicine and Geriatric Research Education and Clinical Center and Research Service Veterans Affairs Medical Center
Miami
FL
USA


Gianluca D'Ippolito
Assistant Professor, Geriatric Research Education and Clinical Center and Research Service
Veterans Affairs Medical Cente
Miami
FL
USA


Juan Domínguez-Bendala
Assistant Professor, Diabetes Research Institute University of Miami Leonard M. Miller School of Medicine
1450 NW 10th Avenue
Miami
FL
USA


M. J. Eaton
Associate professor, Dept. of Veterans Affairs Medical Cente
Miami
FL
USA


Denis English
Professor, Dept. of Neurosurgery
Foundation for Developmental Research University of S. Florida College of Medicine
Tampa
FL
USA


Robin N. Fiore
University of Miami Bioethics Program, University of Miami
FL
USA


Elisa Garbayo
Departments of Medicine and Biochemistry & Molecular Biology
University of Miami Leonard M. Miller School of Medicine Geriatric Research Education and Clinical Center and Research Service VA Medical Center
Miami
FL
USA


Stephan Gluck
Professor, Division of Hematology/Oncology Dept. of Medicine
Sylvester Comprehensive Cancer Center

/
Leonard M. Miller School of Medicine
University of Miami
Miami
FL
USA


Lourdes A. Gomez
Departments of Medicine and Biochemistry & Molecular Biology
University of Miami Leonard M. Miller School of Medicine Geriatric Research Education and Clinical Center and Research Service Veterans Affairs Medical Center
Miami
FL
USA


Kenneth W. Goodman
Professor & Chief, University of Miami Bioethics Program, University of Miami

/
Joshua Hare Professor & Director Interdisciplinary Stem Cell Institute
University of Miami
1120 NW 14th St
Miami
FL
USA


Josh M. Hare
Louis Lemberg Professor & Director
University of Miami Leonard M.Miller School of medicine, Interdisciplinary Stem Cell Institute
Miami
FL , 33101
USA


Alice H. Huang
Dept of Orthopaedic Surgery and Dept. of Bioengineering University of Pennsylvania
McKay Orthopaedic Research Laboratory
Philadelphia
PA
USA


Clark T. Hung
Associate Professor, Dept. of Biomedical Engineering Columbia University
Cellular Engineering Laboratory
New York
NY
USA


Lim Kwong Cheung
Professor, Oral & Maxillofacial Surgery
The Prince Philip Dental Hospital
34 Hospital Road
Hong Kong
SAR
China


Robert L. Mauck
Asistant Professsor, McKay Orthopaedic Research Laboratory Dept of Orthopaedic Surgery and Dept. of Bioengineering
University of Pennsylvania
Philadelphia
PA
USA


Ian McNiece
Professor University of Miami Leonard M. Miler School of Medicine, Interdisciplinary Stem Cell Institute
1120 NW 14th St
Miami
FL
USA


Daniel Pelaez
Ph.D. Candidate, Dept. of Biomedical Engineering
1251 Memorial Drive
Coral Gables
FL
USA


Carmen Rios
Geriatric Research Education and Clinical Center and Research Service
Veterans Affairs Medical Center
Miami
FL
USA


Camillo Ricordi
Professor#x0026; Scientific Director, University of Miami Leonard M. Miller School of Medicin, Diabetes Research Institute
1450 NW 10th Avenue
Miami
FL
USA


Isaac H. Ritter
University of Miami Bioethics Program, University of Miami
FL
USA


Paul C. Schiller
Associate Professor, Departments of Medicine and Biochemistry #x0026; Molecular Biology
University of Miami Miller School of Medicine and Geriatric Research Education and Clinical Center and Research Service VA Medical Center
Miami
FL
USA


Rama S. Verma
Stem Cell and Molecular Biology Laboratory Deptartment of Biotechnology
Institute of Technology-Madras
Chennai
India


Keith A. Webster
Professor Dept. of Molecular and Cellular Pharmacology, Leonard M. Miller School of Medicine
The Vascular Biology Institute, University of Miami
Miami
FL
USA


Eva Widerström-Noga
Associate Professor, The Miami Project to Cure Paralysis
University of Miami Leonard M. Miller School of Medicine
Miami
FL
USA


Stacey Quintero Wolfe
Dept. of Neurological Surgery
University of Miami Leonard M. Miller School of Medicine
Miami
FL
USA


Li Wu Zheng
Assistant Professor, Oral #x0026; Maxillofacial Surgery
The Prince Philip Dental Hospital
34 Hospital Road
Hong Kong
SAR
China


Gary Hin-Fai Yam
Assistant Professor, Department of Ophthalmology & Visual Sciences
The Chinese University of Hong Kong
Hong Kong



Chi Pui Pang
Professor, Department of Ophthalmology & Visual Sciences
The Chinese University of Hong Kong
Hong Kong





RELATED BOOKS

.Frontiers in Stem Cell and Regenerative Medicine Research, Vol. 11.
.Stem Cells in Clinical Application and Productization.
.Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications.
.The Regeneration Promise: The Facts behind Stem Cell Therapies.