Editor: Herman Cheung

Stem Cell & Regenerative Medicine

eBook: US $32 Special Offer (PDF + Printed Copy): US $132
Printed Copy: US $116
Library License: US $128
ISBN: 978-1-60805-697-2 (Print)
ISBN: 978-1-60805-008-6 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080500861100101

Introduction

The potential use of stem cells in transplantation for the purpose of tissue regeneration is an exciting area of research currently undergoing rapid development. Implantation of human embryonic or autologous, ex vivo-expanded adult stem cells, particularly in older individuals, could circumvent the limited availability of organs/tissues as well as prevent complications related to immune rejection and disease transmission. Musculoskeletal tissue degeneration is closely associated with aging. Strategies employing autologous adult MSCs from older individuals for transplantation in order to regenerate their own ailing organ or tissues require that we vigorously define MSCs capacity to maintain growth potential and differentiation potential into the desirable cell lineages. We are currently restricted by the limited knowledge about physical parameters, such as biomechanical forces, that influence MSC growth and differentiation capacities. This is particularly important for MSCs isolated from older individuals, for whom little information is available. This special volume aims to serve as an impetus in generating more interest among stem cell researchers and biotechnologists to improve and develop the cell-based therapies of damaged tissue using stem cells.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, EBSCO.

FOREWORD

- Pp. i
Joshua M. Hare
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PREFACE

- Pp. ii-v (4)
Herman S. Cheung
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CONTRIBUTORS

- Pp. vi-ix (4)
Herman S. Cheung
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Justice and Vulnerability in Human Embryonic Stem Cell Research

- Pp. 1-8 (8)
Isaac H. Ritter, Robin N. Fiore and Kenneth W. Goodman

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Stem Cells and their Contribution to Tissue Repair

- Pp. 9-22 (14)
Carmen Rios, Elisa Garbayo, Lourdes A. Gomez, Kevin Curtis, Gianluca D`’Ippolito and Paul C. Schiller

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The Role of Microenvironment Stromal Cells in Regenerative Medicine

- Pp. 23-28 (6)
Ian McNiece and Joshua Hare

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The Role of Mechanical Forces on Stem Cell Growth and Differentiation

- Pp. 29-39 (11)
Daniel Pelaez, Jason R. Fritz and Herman S. Cheung

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Functional Cartilage Tissue Engineering with Adult Stem Cells: Current Status and Future Directions

- Pp. 40-64 (25)
Alice H. Huang, Clark T. Hung and Robert L. Mauck

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Therapeutic Angiogenesis for Coronary Artery Disease: Clinical Trials of Proteins, Plasmids, Adenovirus and Stem Cells

- Pp. 65-74 (10)
Keith A. Webster

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Use of Progenitor Cells in Pain Management

- Pp. 75-99 (25)
M.J. Eaton, Stacey Quintero Wolfe and Eva Widerström-Noga

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Neural Stem Cells: New Hope for Successful Therapy

- Pp. 100-119 (20)
Denis English, Akshay Anand, Rama S.Verma and Stefan Glück

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Diabetes and Stem Cells

- Pp. 120-139 (20)
Juan Domínguez-Bendala and Camillo Ricordi

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Stem Cells in Dentistry

- Pp. 140-148 (9)
Li Wu Zheng and Lim Kwong Cheung

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Corneal Progenitor Cells and Regenerative Potential

- Pp. 149-159 (11)
Gary Hin-Fai Yam, Sharon Ka-Wai Lee and Chi Pui Pang

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Index

- Pp. 160
Herman S. Cheung
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