Editor: Domenico Ribatti

Recent Advances in Angiogenesis and Antiangiogenesis

eBook: US $54 Special Offer (PDF + Printed Copy): US $135
Printed Copy: US $108
Library License: US $216
ISBN: 978-1-60805-693-4 (Print)
ISBN: 978-1-60805-004-8 (Online)
Year of Publication: 2009
DOI: 10.2174/97816080500481090101

Introduction

The book presents recent advances in the field of angiogenesis and antiangiogenesis. Starting with the hypothesis of Judah Folkman that tumor growth is angiogenesis dependent, this area of research now has a solid scientific foundation. Tumor growth, metastasis, progression, dormancy and apoptosis depend on angiogenesis: several clinical studies have shown a positive correlation between the number of vessels in the tumor, metastasis formation and disease prognosis. A number of approaches have been developed to inhibit tumor angiogenesis, and numerous compounds discovered that inhibit angiogenesis, but only a few of them proved effective in vivo and only a couple of agents were able to induce tumor regression. These and other related developments described in the book should prove to be of interest to a large number of readers wishing to keep abreast with the latest developments in the field.

Contributors

Editor(s):
Domenico Ribatti
Department of Human Anatomy, University of Bari Medical School
Italy




Contributor(s):
Francesco Bertolini
Unit Director, European Institute of Oncology
Milan
Italy


Katiuscia Bonezzi
Assistant, Tumor Angiogenesis Unit Department of Oncology
Mario Negri Institute for Pharmacological Research,
Bergamo
Italy


Paola Braidotti
Assistant Professor, Department of Medicine, Surgery and Dentistry
University of Milan Medical School and “San Paolo” Hospital
Milan
Italy


Federico Bussolino
Department of Oncological Sciences
Full Professor, Institute for Cancer Research and Treatment, University of Torino Medical School
Candiolo
Italy


Anca Maria Cimpean
Assistant Professor, Department of Histology and Molecular Pathology
“Victor Babes” University of Medicine and Pharmacy
Timisoara
Romania


Enrico Crivellato
Assistant Professor, Section of Anatomy, Department of Medical and Morphological Researches
University of Udine Medical School,
Udine
Italy


Maria Fico
Postdoctoral Researcher, Department of Biomedical Sciences and Human Oncology
Bari
Italy


Eberhard Gunsilius
Assistant Professor of Medicine, Tumor Biology & Angiogenesis Laboratory, Department of Internal Medicine V
Innsbruck
Austria


Irene M. Ghobrial
Assistant Professor in Medicine, Department of Medical Oncology
Boston
USA


Chyso Kanthou
Tumour Microcirculation Group, Section of Oncology
Sheffield
UK


Robert S. Kerbel
Full Professor, Sunnybrook Health Science Centre, Molecular and Cellular Biology, Department of Medical Biophysics
Toronto
Canada


Daria Leali
Postdoctoral Researcher, Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology
University of Brescia Medical School
Brescia
Italy


Sandra Liekens
Postdoctoral Researcher, Department of Microbiology and Immunology
Leuven
Belgium


Giuseppe Mangialardi
Postdoctoral Researcher, Department of Biomedical Sciences and Human Oncology
University of Bari Medical School
Bari
Italy


Patrizia Mancuso
Milan
Italy


Michele Moschetta
Postdoctoral Researcher, Department of Biomedical Sciences and Human Oncology
Bari
Italy


Antonella Naldini
Associate Professor, Unit of Neuroimmunophysiology, Department of Physiology
Siena
Italy


Fabio Pastorino
Fellow, Fondazione Italiana per la Lotta al Neuroblastoma, “G. Gaslini” Children’s Hospital
Genoa
Italy


Vito Pistoia
Head, Laboratory of Oncology
G. Gaslini Children’s Hospital
Genoa
Italy


Mirco Ponzoni
Head, Experimental Therapies Unit
Genoa
Italy


Marco Presta
Full professor, Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology
Brescia
Italy


Lizzia Raffaghello
Fellow, Fondazione Italiana per la Lotta al Neuroblastoma
Genoa
Italy


Marius Raica
Full Professor, Department of Histology and Molecular Pathology
Timisoara
Romania


Roberto Ria
Assistant Research, Department of Biomedical Sciences and Human Oncology
Bari
Italy


Domenico Ribatti
Full Professor, Department of Human Anatomy and Histology
Bari
Italy


Aldo M. Roccaro
Instructor in Medicine, Department of Medical Oncology
Boston
USA


Guido Serini
Assistant Researcher, Department of Oncological Sciences
Candiolo
Italy


Yuval Shaked
Assistant Professor, Department of Molecular Pharmacology, Rappaport Faculty of Medicine
Haifa
Israel


Giulia Taraboletti
Head, Tumor Angiogenesis Unit, Department of Oncology
Bergamo
Italy


Gillian M. Tozer
Full Professor, Tumour Microcirculation Group, Section of Oncology
School of Medicine & Biomedical Sciences, University of Sheffield
Sheffield
UK


Gerold Untergasser
Assistant Professor, Tumor Biology & Angiogenesis Laboratory, Department of Internal Medicine V
Innsbruck
Austria


Angelo Vacca
Full Professor, Department of Biomedical Sciences and Human Oncology
Bari
Italy


Donatella Valdembri
Fellow, Department of Oncological Sciences
Candiolo
Italy




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