Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bio-active natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.

The second volume covers the following topics:

• - A review of recent patents and natural products in clinical trials to treat schistosomiasis
• - Natural products: the new intervention regimen for metabolic disorders
• - Fluorine-containing drugs and drug candidates derived from natural products
• - Natural products for the management of cardiovascular diseases
• - Implication of natural compounds for the prevention of ocular diseases

About the Editors:

Prof. Atta-ur-Rahman, Ph.D. in Organic Chemistry from Cambridge University (1968) has 1,232 international publications (45 international patents and 341 books). He received the following awards: Fellow Royal Society (FRS) London (2006), UNESCO Science Prize (1999), Honorary Life Fellow Kings College, Cambridge University (2007), Academician (Foreign Member) Chinese Academy of Sciences (2015), Highest Civil Award for Foreigners of China (Friendship Award, 2014), High Civil Award Austria ("Grosse Goldene Ehrenzeischen am Bande") (2007), Foreign Fellow Chinese Chemical Society (2013), Sc.D. Cambridge University (UK) (1987), TWAS (Italy) Prize (2009). He was the President of Network of Academies of Sciences of Islamic Countries (NASIC), Vice President TWAS (Italy), Foreign Fellow Korean Academy of Science & Technology, President Pakistan Academy of Sciences (2003-2006) and (2011 -- 2014). He was the Federal Minister for Science and Technology of Pakistan (2000 --2002), Federal Minister of Education (2002) and Chairman Higher Education Commission/Federal Minister (2002-2008), Coordinator General of COMSTECH (OIC Ministerial Committee) (1996-2012), and the Editor¬in-Chief of Current Medicinal Chemistry.

Dr. Shazia Anlum is a Professor of the Chemistry Department and the Director of Cholistan Institute of Desert Studies, the Islamia University of Bahawalpur, Pakistan. She is an experienced medicinal and natural product chemist. She has authored and co-authored more than 112 research papers (cumulative Impact Factor: 200), a US patent, has edited 08 books and has published 03 chapters in international books. She has accomplished the synthesis of several naturally occurring aminoglycosides- that can be used as antibiotics. Several students have completed their MS degrees under her supervision and a couple of others are pursing for MS/PhD degrees.

As recognition of her contributions to science, she has been awarded with 03 International awards like Fellowship from Islamic World Academy of Sciences, Postdoctoral fellowship from Ministry of Culture and Education, Spain and a Young Chemist Award from Third World Academy of Sciences, Italy. She also has several national awards to her credit.

Prof. EI-Seedi obtained a Doctorate (Ph.D.) degree in Organic Chemistry, Channel program at Kemisk Institute, Aarhus University, Denmark / Menoufia University, Egypt. Prof. EI-Seedi is a Former Fellow of the Japanese Society of Promotion of Science as a Visiting Assistant Professor, Department of Chemistry, Faculty of Science and Technology, Keio University, Japan. He worked in internationally recognized laboratories including Kunglia Tekniska hogskola (KTH), Stockholm, Sweden, Uppsala Biomedical Center, Uppsala University, Sweden, University of Malaya, and Menoufia University, Egypt. Prof. EI-Seedi has published original papers, reviews, chapters in high level peer-reviewed International Journals including one paper in The Lancet. Most recent awards are: 2017 Price for the best presentation and paper from the Association of Arab Researchers in Bees (AARB) 2017 and 2015: Award from STEFELSEN Foundation for Pharmacognosy: For many years of Scientific Contributions to Pharmacognosy Research and thereby increasing the knowledge about bioactive Natural Products and building contributions with Developing Countries.

Keywords:

Natural products, clinical trials, schistosomiasis, cardiovascular diseases, ocular diseases, bioactive natural products, metabolic disorders

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