Chapter 3

Identifying Drug Structure and Completing the Gaps

Marcus Vinícius Nora de Souza


In this chapter, the exercises below are also based on two themes. The first has an objective of the identification of the structure of the drugs having information of the starting materials and reagents used. This activity also enables the reader to become familiar with different classical chemical transformations used in medicinal chemistry and with varying types of reagents, reaction conditions, and necessary intermediates. In the second theme, the exercises are based on a series of gaps in the synthesis of different drugs. Therefore, it is up to the reader to complete them. This type of exercise is a combination of the themes previously presented. It is necessary to identify the reagents' use, the reaction conditions employed, and the intermediates formed, besides the use of the concept of retrosynthesis.

Total Pages: 70-113 (44)

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