Chapter 1

Plant-Derived Anticancer Compounds Used in Cancer Therapies

Alexander Chota, Blassan P. George and Heidi Abrahamse*

Abstract

Cancer is a serious public health problem that affects both men and women. Globally cancer is one of the leading causes of death. The risk factors associated with cancer development are categorized into intrinsic and extrinsic. The treatment modalities used in the treatment of cancer, such as chemotherapy, radiotherapy, surgery, and targeted therapies have adverse effects either during or after therapy. Currently, plant-derived anticancer compounds are being used in the treatment of various cancers. The variation of these compounds is according to their origin, general classification, and mechanism of action. Various studies have shown that anticancer agents of natural origin have fewer side effects when compared to traditional therapies. Anticancer agents of natural origins are a revolution in the field of cancer research and treatment as they are easy to isolate, cost-effective, and reliable to use. The advantage of anticancer agents of natural origin over synthetic ones and conventional therapeutic options is that their functions are selective and specific to a tumor undergoing treatment. This article is aimed at covering the success of plant-derived anticancer agents in the treatment of cancer, as well as their mechanism of action and the limitations associated with current therapeutic options.

Total Pages: 1-30 (30)

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