Chapter 45

Review on Phyto-Remedy to Manage Diabetes Mellitus

Pratibha Kaushal* and Sanjeev Singh

Abstract

Diabetes Mellitus is a heterogeneous metabolic disorder with various aetiologies that are characterized by chronic hyperglycemia. DM is a consequence of defective metabolism in the body was either cells fail to secrete insulin or insulin per se is inactive. Insulin is a pancreatic hormone responsible for glucose uptake and utilization by cells for energy production. Thus, insulin deficiency renders the cells unable to uptake and utilize glucose for metabolism. DM is majorly categorized into two conditions: Type 1, In this case, there is no enough insulin production by the pancreatic cells (Insulin-dependent). In type II, despite insulin production, the cells fail to respond to the hormone (Insulin Independent), the reason behind the former is not yet clear, but the latter is studied to be a result of obesity or inactivity. Thus, as a consequence of an error in glucose metabolism, it leads to comorbidities, with high glucose concentration in the blood causing damage to the circulatory and excretory system. This condition becomes life-threatening without proper medical care. Type 1 can be treated with an external source of insulin provided to the body. Type II is treated with hypoglycaemic drugs. Along with medicine, other options include an improved lifestyle with proper nutrition and exercise. The number of diabetes patients has been increased today. In the present review article, we have discussed the research reported to show medicinally important plants and plant-derived compounds which have been shown to affect insulin production and glucose intake and utilization in type 2 diabetes patients.

Total Pages: 393-402 (10)

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