Chapter 5


M. Mahmoudi, S. Ghafourian*, B. Badakhsh, H. Kazemian and A. Maleki


The importance of understanding the pathogenesis of infectious agents is in the diagnosis of the diseases and finding new treatments. In the case of P. aeruginosa pathogenesis, the issue is extremely broad and complex. Also, many aspects of its pathogenesis remain unknown to researchers. At a glance, P. aeruginosa causes acute and chronic infections. In addition, P. aeruginosa is an opportunistic bacterium that is highly dangerous in immunocompromised patients. In some cases, it can also threaten human life and causes the death of the patients. The ability of P. aeruginosa to cross the body barriers is so fascinating, which can penetrate the skin and even depths of the bone and joints. Although the pathogenesis of P. aeruginosa depends on many factors, it is attributed to several diseases including, bacteremia, keratitis, pneumonia, bone and joints infection, respiratory tract infection, urinary tract infection, skin and soft tissue infection, ear infection, endocarditis, central nervous system infection, enteric infection, mastitis and, etc. The wide range of diseases caused by P. aeruginosa clearly demonstrated the importance of this bacterium in the fields of medicine.

Total Pages: 44-55 (12)

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