Polarity index in Proteins-A Bioinformatics Tool


Carlos Polanco

DOI: 10.2174/97816810826911160101
eISBN: 978-1-68108-269-1, 2016
ISBN: 978-1-68108-270-7

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, EBSCO.

Polarity is a physico-chemical property that characterizes the electromagnetic stability of a protein and can be used to predict its p...[view complete introduction]
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Polarity Index Method

- Pp. 22-27 (6)

Carlos Polanco


This chapter will describe one supervised algorithm that is frequently used to predict the function of proteins, the quantitative structure-activity relationship model (QSAR). I will discuss its advantages and disadvantages, and I will present a model called the polarity index method. This model shows a high degree of efficiency in predicting the main function of peptides and proteins by inspecting the linear sequence of macromolecules to evaluate a single physico-chemical property, polarity.

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