Fundamentals of Systems Analysis and Modeling of Biosystems and Metabolism

by

Kazuyuki Shimizu, Yu Matsuoka

DOI: 10.2174/97816810808641150101
eISBN: 978-1-68108-086-4, 2015
ISBN: 978-1-68108-087-1



Indexed in: EBSCO.

An understanding of biological systems at cellular and molecular levels helps researchers to model cellular behavior in different expe...[view complete introduction]
US $
Buy Personal eBook
99
Order Library eBook
396
Order Printed Copy
*119
Order PDF + Printed Copy (Special Offer)
*168

*(Excluding Mailing and Handling)

🔒Secure Checkout Personal information is secured with SSL technology

Kinetic Modeling for the Main Metabolic Pathways

- Pp. 133-186 (54)

Kazuyuki Shimizu and Yu Matsuoka

Abstract

Kinetic models for the main metabolic pathways such as glycolysis, TCA cycle, pentose phosphate pathway together with anaplerotic pathways and gluconeogenic pathways are explained. Kinetic models for substrate uptake pathways such as glucose PTS, glycerol uptake pathways, and xylose assimilating pathways are then explained. Kinetic models for the fermentation pathways under anaerobic condition are also explained. Moreover, kinetic models for amino acid synthetic pathways such as glutamic acid/ glutamine synthetic pathways and lysine synthetic pathways are explained. Unlike flux balance analysis based on the stoichiometric constraints, kinetic modeling approach based on enzymatic reactions for the metabolic pathways can be easily extended for the inclusion of enzyme level and transcriptional regulations, and the kinetic models can reasonably express the dynamics.

Purchase Chapter  Book Details

Advertisement


Webmaster Contact: info@benthamscience.net Copyright © 2019 Bentham Science