Fungal Biotechnology for Biofuel Production

Book Series: Mycology: Current and Future Developments

Volume 1


Roberto N. Silva

DOI: 10.2174/97816810807411150101
eISBN: 978-1-68108-074-1, 2016
ISBN: 978-1-68108-075-8
ISSN: 2452-0772 (Print)
ISSN: 2452-0780 (Online)

Indexed in: EBSCO.

Mycology: Current and Future Development is a book series that brings together t...[view complete introduction]
US $
Buy Personal Book
Order Library Book
Order Printed Copy
Order PDF + Printed Copy (Special Offer)

*(Excluding Mailing and Handling)

🔒Secure Checkout Personal information is secured with SSL technology
Download Flyer

Systems and Synthetic Biology Approaches for Fungal Engineering

- Pp. 395-418 (24)

Gerardo Ruiz Amores, María-Eugenia Guazzaroni, Letícia Magalhães Arruda and Rafael Silva-Rocha


Filamentous fungi are remarkable organisms that are naturally specialized in deconstructing plant biomass. This feature explains their tremendous potential for biofuel production from renewable sources. However, organisms from this group need to be engineered to make them compatible with standard operating procedures of the industry and to optimize their applications in the field of biotechnology. Here, we discuss the development of new tools and approaches for the engineering of fungi for biotech applications such as the production of biofuels. These tools include not only next-generation “omics” tools to obtain deeper insight into the molecular biology of filamentous fungi, but also novel engineering approaches for the genetic modification of these organisms to generate highly efficient cell factories. The first set of tools, in framework of Systems Biology, targets understanding how these fascinating organisms are able to integrate multi-level environmental information in order to coordinate gene expression and protein production in response to changing conditions. The second approach, in the context of Synthetic Biology, provides physical and conceptual tools that allow the genetic modification of fungi, mainly through the construction of synthetic promoters for the expression of heterologous genes in these organisms and either expanding their capabilities or reshaping their regulatory networks. Finally, we discuss some new directions that have been initiated or should be addressed in future work in order to fill gaps still existing in the field.

Purchase Chapter  Book Details


Special New Year Discount

Webmaster Contact: Copyright © 2019 Bentham Science