Chapter 1

Important Historical Facts of Tuberculosis Treatment and Drug Development

Marcus V.N. de Souza

Abstract

In this chapter will be highlight some important historical facts of tuberculosis treatment and drug development, such as theories, studies and treatment of TB between 17-20<sup>th</sup> Century, historical aspects of TB drug discovery, side effects, fixed-dose combinations, causes of the resurgence of TB, AIDS, multi-drug-resistant tuberculosis (MDR TB) and extensive-drug- resistant (XDR).

Total Pages: 3-37 (35)

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