Chapter 10

Application of Monoterpenoids and their Derivatives Against CNS Disorders

Alla V. Pavlova, Konstantin P. Volcho and Tatyana G. Tolstikova


Monoterpenoids and their derivatives play an important role in the creation of new bioactive substances including drugs. Many of these compounds possess substantial CNS activities such as antinociceptive, neuroprotective, anticonvulsant. In the past decades, interest in investigating the possibility of using monoterpenoids for the development of new drugs has increased significantly due to improvement of both chemical methods of modification of natural compounds, and a substantial deficit of breakthrough research to create drugs to treat diseases associated with central nervous system. The review covers the literature on monoterpenoids and their derivatives exhibit various types of CNS activities published up to early 2012.

Total Pages: 334-380 (47)

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