Antibodies Applications and New Developments


Eline P. Meulenberg

DOI: 10.2174/97816080526461120101
eISBN: 978-1-60805-264-6, 2012
ISBN: 978-1-60805-586-9

Indexed in: Scopus, Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, EBSCO.

Antibodies Applications and New Developments is an overview of the current developments of techniques and methods rel...[view complete introduction]
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Antibodies as Bioanalytical Tools in Food Analysis

- Pp. 68-75 (8)

Georg Mahlknecht


With new developments in agriculture and food production in the past two decades, bioanalytical detection of toxins and allergens in foods became a challenging task. In addition, efficient validation and labelling of food products demand reliable technical approaches. Complex, heterogeneous matrices and low amounts of specific analytes complicate detection and characterization of harmful substances in food. A highly relevant tool to achieve this goal is represented by several immunochemical approaches, based on antibody technology. Different types of antibodies have been developed, which are characterized by high affinity and specificity. Although, alternative methods have been introduced into food analysis (e.g., mass-spectrometry and PCR), antibodies still play a key role, especially in detection and characterization of allergens. In this chapter, I discuss basic immunochemical methods of food analysis based on antibody technologies. The increasing importance of establishing suitable detection schemes for several allergens (e.g., allergens from peanut and soy) in an immunoanalytical approach, will be particularly emphasized.

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