Chapter 8

Transcription Factors in Hematological Malignancies

Estela Maria Novak and Durvanei Augusto Maria


Transcription factors are key regulators of the pattern of gene expression in a cell and directly control central processes such as proliferation, survival, self-renewal, and invasion. Alterations in the mechanisms that normally control these functions can lead to hematological malignancies. This chapter will describe the highlights of the main transcription factors in hematological malignancies.

Total Pages: 78-102 (25)

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