Treatise on Ocular Drug Delivery

by

Ashim K. Mitra

DOI: 10.2174/97816080517551130101
eISBN: 978-1-60805-175-5, 2013
ISBN: 978-1-60805-347-6



Indexed in: EBSCO.

A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing e...[view complete introduction]
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Biodegradable Polymers for Ophthalmic Applications

- Pp. 96-113 (18)

Viral Tamboli, Sulabh Patel, Gyan P. Mishra and Ashim K. Mitra

Abstract

Biodegradable polymers (both synthetic and natural) have been extensively explored for ophthalmic applications. These biomaterials are mainly biocompatible and biodegradable in nature. Moreover, different biodegradable polymers have different physico-chemical properties which can further be modulated to formulate desirable drug products. A wide range of ocular drug delivery systems such as implants, inserts, corneal shields, contact lenses, micelles, nanoparticles, microparticles, liposomes, dendrimers and stimuli sensitive hydrogels can be formulated with biodegradable polymers. Moreover, controlled drug delivery systems made up of biodegradable polymers can deliver a variety of therapeutic molecules including hydrophilic and hydrophobic small and macromolecules for prolonged periods to the targeted ocular tissues. In this chapter, we reviewed various synthetic and natural biodegradable polymers applied to ocular drug delivery.

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