Chapter 3

Avastin and Malignant Gliomas: Is there a Role?

Teri N. Kreisl

Abstract

<p>Bevacizumab is the first new drug approved for malignant glioma in a decade and demonstrates the potential for antiangiogenic therapy in the management of these patients. It has demonstrated improved radiographic response and progression free survival rates compared to historical controls as monotherapy. Bevacizumab has also been shown to improve patient symptoms of disease and decrease steroid requirements contributing to improved quality of life for glioma patients. Optimal combinations with other standard and targeted therapies are under investigation, as well as new imaging techniques to evaluate response to therapy, motivated in part by concerns over suspected increase potential for tumor invasion.</p>

Total Pages: 12-18 (7)

Purchase Chapter  Book Details

RELATED BOOKS

.Breast Cancer: Current Trends in Molecular Research.
.Artificial Intelligence Based Cancer Nanomedicine: Diagnostics, Therapeutics and Bioethics.
.Colorectal Cancer Diagnosis and Therapeutic Updates.
.Nanotherapeutics for the Treatment of Hepatocellular Carcinoma.